Cyclobenzaprine: Uses, Interactions, Mechanism of Action DrugBank Online
Substance abuse can occur at any time, for anyone, but recovery is possible with the right support. Furthermore, The Drug Abuse Warning Network (DAWN) reported in 2011 that more than 11,000 individuals received care from emergency departments for misusing cyclobenzaprine. If you experience withdrawal symptoms when not using cyclobenzaprine, or as the drug wears off, this could be a clear indication that you are addicted to Flexeril.
In a small number of people, cyclobenzaprine and methocarbamol can cause more serious adverse effects such as allergic reactions with severe rash, swelling, and trouble breathing. If you experience these adverse effects, please seek emergency medical attention. However, one drug might be more effective for you than another. Robaxin is the brand name of the generic medication called methocarbamol. It was developed in the 1960s to treat pain and provide relief from muscle spasms. It is also believed that Robaxin relaxes the muscle by having depressive effects on the central nervous system.
Cyclobenzaprine relieves skeletal muscle spasms of local origin without interfering with muscle function. In preclinical research, cyclobenzaprine reduced skeletal muscle hyperactivity. Research indicates that it primarily acts within the central nervous system in the brain stem. An increased tolerance increases the chances of experiencing a Flexeril overdose. Much like most prescription drugs, abusing Flexeril can quickly turn into a fully-fledged addiction. Cyclobenzaprine comes as a tablet and an extended-release capsule to take by mouth.
- Cyclobenzaprine caused slight to moderate increase in heart rate in animals.
- Side effects of tricyclic antidepressants include drowsiness, blurred vision, and drop in blood pressure when standing up after sitting (20).
- As the substance can result in drowsiness, it is recommended to avoid driving or using heavy machinery until you are familiar with the effects.
- Those with fibromyalgia may experience widespread muscle pain as well as problems with sleep, fatigue, and mood.
- However, cyclobenzaprine is one of the most studied muscle relaxers with strong evidence for its effectiveness.
Do not use it later for another condition unless your doctor directs you to do so. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). According to systematic reviews, almost all muscle relaxers are comparable in effectiveness.
What are the possible drug interactions of cyclobenzaprine or methocarbamol?
Anyone with a history of substance abuse should mention this medical history to their doctor. Muscle relaxants are some of the most commonly prescribed medications to treat back pain and other strains or sprains. Robaxin (methocarbamol) and Flexeril (cyclobenzaprine) are examples of skeletal muscle relaxants (SMRs) that your healthcare provider may prescribe if you experience muscle pain.
By preventing serotonin transmission, cyclobenzaprine alleviates pain by reducing the number of pain signals that reach the central nervous system. Dogs can take muscle relaxers such as Flexeril for pain relief. Veterinarians suggest short-term treatments with Flexeril for dogs and cats with acute muscle spasms.
Interactions
A Flexeril overdose can cause severe health problems such as cardiac arrest, dangerously low blood pressure, and seizures. Central nervous system depression, seizures, heart attack, and even death can occur. A post-marketing surveillance program was carried out in 7607 patients with acute can you take baclofen with flexeril musculoskeletal disorders, and included 297 patients treated with FLEXERIL 10 mg for 30 days or longer. The overall effectiveness of FLEXERIL was similar to that observed in the double-blind controlled studies; the overall incidence of adverse effects was less (see ADVERSE REACTIONS).
This can help keep levels of this drug from building up too much in your body. If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or pharmacist. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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It is also important information to carry with you in case of emergencies. Generic methocarbamol is around $6.25 for 30 tablets of the 500mg dose with a BuzzRx drug discount card. Brand name Robaxin is approximately $95 for 30 tablets of the 750mg dose with a BuzzRx savings card. Generic cyclobenzaprine may be under $0.50 for 30 tablets of the 10mg dose through the BuzzRx discount program. Also, methocarbamol and cyclobenzaprine are not recommended in pregnant women, elderly adults, and young children. Methocarbamol can be used for long or short-term treatment as advised by a doctor.
On the other hand, cyclobenzaprine is generally not prescribed for longer than two or three weeks. As an illegal drug, cyclobenzaprine is known by the street names mellow yellow or cyclone. While not as popular among recreational drug users, it is known by addicts with experience abusing prescription drugs and a desire for sedative highs. Cyclobenzaprine—fully called cyclobenzaprine hydrochloride, or C20H22ClN—was first synthesized in 1961 by the pharmaceutical company Merck & Company. It is chemically related to tricyclic antidepressants, an early form of antidepressants invented in the 1950s. Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function.